Cultures of blood and pleural fluid and serologic titers are the most specific. Background. S. pneumoniae UAT; It is an immunochromatographic assay to detect the C polysaccharide in the bacterial cell wall; The sensitivity of the S. pneumoniae UAT compared against the standard for diagnosis (blood, sputum and pleural fl uid cultures) ranged from 82 to 88% (95% CI 74-95) The specifi city was 96 to 97% (95% CI 86.5—99.5). There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia (HCAP). 1994 Sep;9(3):166-79. Therefore, our aim was to evaluate the utility of qPCR as a useful method for etiologic diagnoses of MRSA-based pneumonia. Every patient underwent both procedures, in a formally randomized fashion. Laboratory-based diagnosis of pneumonia currently considers S. pneumoniae, largely because of the exclusion of other potential aetiologies. When the 10 alpha-streptococci that showed the strongest crossreactions and ten pneumococci representing different types were tested in different concentrations the absorbance values were lower for most alpha-streptococci compared with the pneumococci. Epub 2006 Sep 7. The studies related to pneumonias in children with underlying disease, such as acquired or congenital immunodeficiencies and mycobacterial diseases, have not been described. From about one-third to two-thirds of cases of pneumonia can be attributed to a specific etiology depending on which culture, antigen detection and specialized serologic techniques, some of which … Concerns about treatment recommendations, on the one hand, and antibiotic stewardship, on the other, motivated this review of the medical literature on the etiology of CAP. The collection of alpha-streptococci consisted of 90 fresh clinical isolates and 30 stock strains. Clinicians traditionally have used the chest radiograph as the gold standard in the diagnosis of pneumonia, but … Eletu SD, Sheppard CL, Rose S, Smith K, Andrews N, Lim WS, Litt DJ, Fry NK. The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. Unable to load your collection due to an error, Unable to load your delegates due to an error. Objectives:: The impact of ICU-acquired pneumonia without etiologic diagnosis on patients' outcomes is largely unknown. [Article in Spanish] Martínez Vázquez C, Pedreira JD, Cabré-Verdiel J, Miquel C, de Buen ML, Gallart MT, Guardia J. Clipboard, Search History, and several other advanced features are temporarily unavailable. Although pneumonia is widespread, its etiology usually remains unknown. J Clin Microbiol. Lasocki S, Scanvic A, Le Turdu F, Restoux A, Mentec H, Bleichner G, Sollet JP. The clinical history is helpful in distinguishing community- from hospital-acquired pneumonia and in identifying patients who are immunosuppressed or aspiration prone. Direct means of obtaining diagnostic material in patients with pneumonia include percutaneous lung aspiration, transbronchial lung biopsy, video-assisted thoracoscopy, and open lung biopsy. Tickborne rickettsial illnesses: Features, diagnosis, & treatment: Take Quiz: Etiologic diagnosis of chronic pneumonia by symptoms: Take Quiz: Helicobacter pylori therapy: Minimizing antibiotic misuse: Take Quiz: No horsing around: Zoonotic diseases associated with horses: Take Quiz: Diagnosis of community-acquired pneumonia: Take Quiz 1980 May 3;124(18):697-701. Extrapulmonary. Prevention and treatment information (HHS). Next-generation sequencing of microbial DNA directly from patient samples may improve diagnostic accuracy for guiding antibiotic prescriptions. Please enable it to take advantage of the complete set of features! We systematically searched the Medline, Embase, Science Direct, Scopus and LILACS … Clipboard, Search History, and several other advanced features are temporarily unavailable. Cultures of blood and pleural fluid and serologic titers are the most specific. Proper Previous clinical. Pitfalls, however, abound. Meanwhile, prevention measures should be applied. 1996 Apr;14(4):255-7. coccal pneumonia have made faster diagnostic techniques necessary. Design: Prospective study in consecutive patients with high probability of VAP. This paper describes challenges in etiologic diagnosis and treatment of childhood community-acquired pneumonia and the means of addressing some of them.. Microbiologic diagnosis. Holmberg H, Holme T, Krook A, Olsson T, Sjöberg L, Sjögren AM. The value and complications of percutaneous transthoracic lung aspiration for the etiologic diagnosis of community-acquired pneumonia. NEJM Journal Watch reviews over 250 scientific and medical journals to present important clinical research findings and insightful commentary. doi: 10.1099/acmi.0.000094. The etiologic agent was identified in 284 (50%) of the 570 cases of lobar pneumonia and in 515 (55%) of the 944 cases of bronchopneumonia. Gram stain and culture of sputum or ETSA constitute the mainstay for obtaining an etiologic diagnosis when blood cultures are negative. National Library of Medicine situation regarding pneumonia in pediatric patients worldwide. diagnosis [di″ag-no´sis] 1. determination of the nature of a cause of a disease. The need for invasive diagnostic procedures is likely to increase in the future, necessitating greater knowledge of the relative risks and merits of each procedure on the part of all physicians who treat patients with pneumonia. Design: Prospective observational study. Bethesda, MD 20894, Copyright Strong crossreactions were observed with 36% of the alpha-streptococci and with two of 11 Staphylococcus aureus strains. A variety of specimen types may be obtained, including bronchial washes or brushes, protected specimen brushing, bronchoalveolar lavage, and transbronchial biopsies. General management for … Proper Privacy, Help 8600 Rockville Pike Development of new diagnostic methods has been encouraged. adj., adj diagnos´tic. Treatment of community-acquired pneumonias. Detection of C polysaccharide in Streptococcus pneumoniae in the sputa of pneumonia patients by an enzyme-linked immunosorbent assay. Setting: doi: 10.1371/journal.pone.0033620. Polymerase chain reaction (PCR) of nasopharyngeal swabs: Am J Med. Enferm Infecc Microbiol Clin. 8600 Rockville Pike Eletu SD, Sheppard CL, Thomas E, Smith K, Daniel P, Litt DJ, Lim WS, Fry NK. pneumoniae was 81.08 % to aztreonam, and the lowest drug resistance rate was 0.00 % to imipenem. 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